Cryptotanshinone enhances the effect of Arsenic trioxide in treating liver cancer cell by inducing apoptosis through downregulating phosphorylated- STAT3 in vitro and in vivo

BACKGROUND: Arsenic trioxide (ATO) is approved for treating terminal-stage liver cancer in China. Cryptotanshinone (CT), a STAT3 inhibitor, has exhibited certain anti-tumor potency; however, the use of CT enhanced ATO for treating liver cancer has not been reported. Here we try to elucidate how CT c...

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Detalles Bibliográficos
Autores principales: Shen, Li, Zhang, Guangshun, Lou, Zhaohuan, Xu, Guanhua, Zhang, Guangji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5303285/
https://www.ncbi.nlm.nih.gov/pubmed/28187727
http://dx.doi.org/10.1186/s12906-016-1548-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5303285/
https://www.ncbi.nlm.nih.gov/pubmed/28187727
http://dx.doi.org/10.1186/s12906-016-1548-4

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