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The potential neuroprotective role of a histone deacetylase inhibitor, sodium butyrate, after neonatal hypoxia-ischemia

BACKGROUND: Histone deacetylase inhibitor (HDACi), sodium butyrate (SB), has been shown to be neuroprotective in adult brain injury models. Potential explanation for the inhibitor action involves among others reduced inflammation. We therefore anticipated that SB will provide a suitable option for b...

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Detalles Bibliográficos
Autores principales: Jaworska, Joanna, Ziemka-Nalecz, Malgorzata, Sypecka, Joanna, Zalewska, Teresa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5303300/
https://www.ncbi.nlm.nih.gov/pubmed/28187734
http://dx.doi.org/10.1186/s12974-017-0807-8