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Identification of Predictive DNA Methylation Biomarkers for Chemotherapy Response in Colorectal Cancer

Resistance to 5-Fluorouracil (5-FU) is a major obstacle to the successful treatment of colorectal cancer (CRC) and posed an increased risk of recurrence. DNA methylation has been suggested as one of the underlying mechanisms for recurrent disease and its contribution to the development of drug resis...

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Detalles Bibliográficos
Autores principales: Baharudin, Rashidah, Ab Mutalib, Nurul-Syakima, Othman, Sri N., Sagap, Ismail, Rose, Isa M., Mohd Mokhtar, Norfilza, Jamal, Rahman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5303736/
https://www.ncbi.nlm.nih.gov/pubmed/28243201
http://dx.doi.org/10.3389/fphar.2017.00047