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Identification of Predictive DNA Methylation Biomarkers for Chemotherapy Response in Colorectal Cancer
Resistance to 5-Fluorouracil (5-FU) is a major obstacle to the successful treatment of colorectal cancer (CRC) and posed an increased risk of recurrence. DNA methylation has been suggested as one of the underlying mechanisms for recurrent disease and its contribution to the development of drug resis...
Autores principales: | Baharudin, Rashidah, Ab Mutalib, Nurul-Syakima, Othman, Sri N., Sagap, Ismail, Rose, Isa M., Mohd Mokhtar, Norfilza, Jamal, Rahman |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5303736/ https://www.ncbi.nlm.nih.gov/pubmed/28243201 http://dx.doi.org/10.3389/fphar.2017.00047 |
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