Nifedipine Increases Iron Content in WKPT-0293 Cl.2 Cells via Up-Regulating Iron Influx Proteins

Nifedipine was reported to enhance urinary iron excretion in iron overloaded mice. However, it remains unknown how nifedipine stimulates urinary iron excretion in the kidney. We speculated that nifedipine might inhibit the TfR1/ DMT1 (transferrin receptor 1/divalent metal transporter1)-mediated iron...

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Detalles Bibliográficos
Autores principales: Yu, Shuang-Shuang, Jiang, Li-Rong, Ling, Yan, Qian, Zhong-Ming, Zhou, Yu-Fu, Li, Juan, Ke, Ya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5303744/
https://www.ncbi.nlm.nih.gov/pubmed/28243203
http://dx.doi.org/10.3389/fphar.2017.00060

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5303744/
https://www.ncbi.nlm.nih.gov/pubmed/28243203
http://dx.doi.org/10.3389/fphar.2017.00060

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