A CAF40-binding motif facilitates recruitment of the CCR4-NOT complex to mRNAs targeted by Drosophila Roquin

Human (Hs) Roquin1 and Roquin2 are RNA-binding proteins that promote mRNA target degradation through the recruitment of the CCR4-NOT deadenylase complex and are implicated in the prevention of autoimmunity. Roquin1 recruits CCR4-NOT via a C-terminal region that is not conserved in Roquin2 or in inve...

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Detalles Bibliográficos
Autores principales: Sgromo, Annamaria, Raisch, Tobias, Bawankar, Praveen, Bhandari, Dipankar, Chen, Ying, Kuzuoğlu-Öztürk, Duygu, Weichenrieder, Oliver, Izaurralde, Elisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5303829/
https://www.ncbi.nlm.nih.gov/pubmed/28165457
http://dx.doi.org/10.1038/ncomms14307

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5303829/
https://www.ncbi.nlm.nih.gov/pubmed/28165457
http://dx.doi.org/10.1038/ncomms14307

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