Fibrillar Type I Collagen Enhances the Differentiation and Proliferation of Myofibroblasts by Lowering α2β1 Integrin Expression in Cardiac Fibrosis

Many studies have shown that α2β1 integrin plays an important role in the development of cardiac fibrosis. However, the mechanism of how α2β1 integrin regulates the differentiation and proliferation of myofibroblasts in cardiac fibrosis through fibrillar collagen (FC) remains uncertain. We establish...

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Detalles Bibliográficos
Autores principales: Hong, Jian, Chu, Ming, Qian, Lijun, Wang, Junhong, Guo, Yan, Xu, Di
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5303846/
https://www.ncbi.nlm.nih.gov/pubmed/28251149
http://dx.doi.org/10.1155/2017/1790808

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5303846/
https://www.ncbi.nlm.nih.gov/pubmed/28251149
http://dx.doi.org/10.1155/2017/1790808

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