Axon degeneration induces glial responses through Draper-TRAF4-JNK signalling

Draper/Ced-1/MEGF-10 is an engulfment receptor that promotes clearance of cellular debris in C. elegans, Drosophila and mammals. Draper signals through an evolutionarily conserved Src family kinase cascade to drive cytoskeletal rearrangements and target engulfment through Rac1. Glia also alter gene...

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Detalles Bibliográficos
Autores principales: Lu, Tsai-Yi, MacDonald, Jennifer M., Neukomm, Lukas J., Sheehan, Amy E., Bradshaw, Rachel, Logan, Mary A., Freeman, Marc R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5303877/
https://www.ncbi.nlm.nih.gov/pubmed/28165006
http://dx.doi.org/10.1038/ncomms14355

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5303877/
https://www.ncbi.nlm.nih.gov/pubmed/28165006
http://dx.doi.org/10.1038/ncomms14355

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