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Concurrent Hypermethylation of SFRP2 and DKK2 Activates the Wnt/β-Catenin Pathway and Is Associated with Poor Prognosis in Patients with Gastric Cancer

Aberrant hypermethylation of Wnt antagonists has been observed in gastric cancer. A number of studies have focused on the hypermethylation of a single Wnt antagonist and its role in regulating the activation of signaling. However, how the Wnt antagonists interacted to regulate the signaling pathway...

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Detalles Bibliográficos
Autores principales: Wang, Hao, Duan, Xiang-Long, Qi, Xiao-Li, Meng, Lei, Xu, Yi-Song, Wu, Tong, Dai, Peng-Gao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Molecular and Cellular Biology 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5303888/
https://www.ncbi.nlm.nih.gov/pubmed/28152305
http://dx.doi.org/10.14348/molcells.2017.2245