Concentration-dependent oligomerization of an alpha-helical antifreeze polypeptide makes it hyperactive

A supersoluble 40-residue type I antifreeze protein (AFP) was discovered in a righteye flounder, the barfin plaice (bp). Unlike all other AFPs characterized to date, bpAFP transitions from moderately-active to hyperactive with increasing concentration. At sub-mM concentrations, bpAFP bound to pyrami...

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Detalles Bibliográficos
Autores principales: Mahatabuddin, Sheikh, Hanada, Yuichi, Nishimiya, Yoshiyuki, Miura, Ai, Kondo, Hidemasa, Davies, Peter L., Tsuda, Sakae
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5304152/
https://www.ncbi.nlm.nih.gov/pubmed/28211917
http://dx.doi.org/10.1038/srep42501

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5304152/
https://www.ncbi.nlm.nih.gov/pubmed/28211917
http://dx.doi.org/10.1038/srep42501

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