Myotonic dystrophy type 1 patient-derived iPSCs for the investigation of CTG repeat instability

Myotonic dystrophy type 1 (DM1) is an autosomal-dominant multi-system disease caused by expanded CTG repeats in dystrophia myotonica protein kinase (DMPK). The expanded CTG repeats are unstable and can increase the length of the gene with age, which worsens the symptoms. In order to establish a huma...

Descripción completa

Detalles Bibliográficos
Autores principales: Ueki, Junko, Nakamori, Masayuki, Nakamura, Masahiro, Nishikawa, Misato, Yoshida, Yoshinori, Tanaka, Azusa, Morizane, Asuka, Kamon, Masayoshi, Araki, Toshiyuki, Takahashi, Masanori P., Watanabe, Akira, Inagaki, Nobuya, Sakurai, Hidetoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5304155/
https://www.ncbi.nlm.nih.gov/pubmed/28211918
http://dx.doi.org/10.1038/srep42522

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5304155/
https://www.ncbi.nlm.nih.gov/pubmed/28211918
http://dx.doi.org/10.1038/srep42522

Ejemplares similares