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Activating Killer Immunoglobulin Receptors and HLA-C: a successful combination providing HIV-1 control

Several studies demonstrated a relevant role of polymorphisms located within the HLA-B and -C loci and the Killer Immunoglobulin Receptors (KIRs) 3DL1 and 3DS1 in controlling HIV-1 replication. KIRs are regulatory receptors expressed at the surface of NK and CD8+ T-cells that specifically bind HLA-A...

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Detalles Bibliográficos
Autores principales: Malnati, Mauro S., Ugolotti, Elisabetta, Monti, Maria Cristina, Battista, Davide De, Vanni, Irene, Bordo, Domenico, Sironi, Francesca, Larghero, Patrizia, Marco, Eddi Di, Biswas, Priscilla, Poli, Guido, Vicenzi, Elisa, Riva, Agostino, Tarkowski, Maciej, Tambussi, Giuseppe, Nozza, Silvia, Tripodi, Gino, Marras, Francesco, Maria, Andrea De, Pistorio, Angela, Biassoni, Roberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5304173/
https://www.ncbi.nlm.nih.gov/pubmed/28211903
http://dx.doi.org/10.1038/srep42470