Vascular smooth muscle cell glycocalyx mediates shear stress-induced contractile responses via a Rho kinase (ROCK)-myosin light chain phosphatase (MLCP) pathway

The vascular smooth muscle cells (VSMCs) are exposed to interstitial flow induced shear stress that may be sensed by the surface glycocalyx, a surface layer composed primarily of proteoglycans and glycoproteins, to mediate cell contraction during the myogenic response. We, therefore, attempted to el...

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Detalles Bibliográficos
Autores principales: Kang, Hongyan, Liu, Jiajia, Sun, Anqiang, Liu, Xiao, Fan, Yubo, Deng, Xiaoyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5304191/
https://www.ncbi.nlm.nih.gov/pubmed/28191820
http://dx.doi.org/10.1038/srep42092

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5304191/
https://www.ncbi.nlm.nih.gov/pubmed/28191820
http://dx.doi.org/10.1038/srep42092

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