Ran-dependent TPX2 activation promotes acentrosomal microtubule nucleation in neurons

The microtubule (MT) cytoskeleton is essential for the formation of morphologically appropriate neurons. The existence of the acentrosomal MT organizing center in neurons has been proposed but its identity remained elusive. Here we provide evidence showing that TPX2 is an important component of this...

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Detalles Bibliográficos
Autores principales: Chen, Wen-Shin, Chen, Yi-Ju, Huang, Yung-An, Hsieh, Bing-Yuan, Chiu, Ho-Chieh, Kao, Pei-Ying, Chao, Chih-Yuan, Hwang, Eric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5304320/
https://www.ncbi.nlm.nih.gov/pubmed/28205572
http://dx.doi.org/10.1038/srep42297

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5304320/
https://www.ncbi.nlm.nih.gov/pubmed/28205572
http://dx.doi.org/10.1038/srep42297

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