Rapid differentiation of human pluripotent stem cells into functional neurons by mRNAs encoding transcription factors

Efficient differentiation of human pluripotent stem cells (hPSCs) into neurons is paramount for disease modeling, drug screening, and cell transplantation therapy in regenerative medicine. In this manuscript, we report the capability of five transcription factors (TFs) toward this aim: NEUROG1, NEUR...

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Detalles Bibliográficos
Autores principales: Goparaju, Sravan Kumar, Kohda, Kazuhisa, Ibata, Keiji, Soma, Atsumi, Nakatake, Yukhi, Akiyama, Tomohiko, Wakabayashi, Shunichi, Matsushita, Misako, Sakota, Miki, Kimura, Hiromi, Yuzaki, Michisuke, Ko, Shigeru B. H., Ko, Minoru S. H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5304326/
https://www.ncbi.nlm.nih.gov/pubmed/28205555
http://dx.doi.org/10.1038/srep42367

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5304326/
https://www.ncbi.nlm.nih.gov/pubmed/28205555
http://dx.doi.org/10.1038/srep42367

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