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Immune regulator ABIN1 suppresses HIV-1 transcription by negatively regulating the ubiquitination of Tat
BACKGROUND: A20-binding inhibitor of NF-κB activation (ABIN1), an important immune regulator, was previously shown to be involved in HIV-1 replication. However, the reported studies done with overexpressed ABIN1 provided controversial results. RESULTS: Here we identified ABIN1 as a suppressor of HIV...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5304394/ https://www.ncbi.nlm.nih.gov/pubmed/28193275 http://dx.doi.org/10.1186/s12977-017-0338-5 |