Immune regulator ABIN1 suppresses HIV-1 transcription by negatively regulating the ubiquitination of Tat

BACKGROUND: A20-binding inhibitor of NF-κB activation (ABIN1), an important immune regulator, was previously shown to be involved in HIV-1 replication. However, the reported studies done with overexpressed ABIN1 provided controversial results. RESULTS: Here we identified ABIN1 as a suppressor of HIV...

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Detalles Bibliográficos
Autores principales: Chen, Shiyou, Yang, Xiaodan, Cheng, Weijia, Ma, Yuhong, Shang, Yafang, Cao, Liu, Chen, Shuliang, Chen, Yu, Wang, Min, Guo, Deyin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5304394/
https://www.ncbi.nlm.nih.gov/pubmed/28193275
http://dx.doi.org/10.1186/s12977-017-0338-5

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