Fabrication and in vitro/in vivo evaluation of amorphous andrographolide nanosuspensions stabilized by d-α-tocopheryl polyethylene glycol 1000 succinate/sodium lauryl sulfate

Andrographolide (ADG) is a diterpenoid isolated from Andrographis paniculata with a wide spectrum of biological activities, including anti-inflammatory, anticancer and hepatoprotective effects. However, its poor water solubility and efflux by P-glycoprotein have resulted in lower bioavailability. In...

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Detalles Bibliográficos
Autores principales: Qiao, Hongzhi, Chen, Lihua, Rui, Tianqi, Wang, Jingxian, Chen, Ting, Fu, Tingming, Li, Junsong, Di, Liuqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2017
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5304988/
https://www.ncbi.nlm.nih.gov/pubmed/28223797
http://dx.doi.org/10.2147/IJN.S120887

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5304988/
https://www.ncbi.nlm.nih.gov/pubmed/28223797
http://dx.doi.org/10.2147/IJN.S120887

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