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Fabrication and in vitro/in vivo evaluation of amorphous andrographolide nanosuspensions stabilized by d-α-tocopheryl polyethylene glycol 1000 succinate/sodium lauryl sulfate
Andrographolide (ADG) is a diterpenoid isolated from Andrographis paniculata with a wide spectrum of biological activities, including anti-inflammatory, anticancer and hepatoprotective effects. However, its poor water solubility and efflux by P-glycoprotein have resulted in lower bioavailability. In...
Autores principales: | Qiao, Hongzhi, Chen, Lihua, Rui, Tianqi, Wang, Jingxian, Chen, Ting, Fu, Tingming, Li, Junsong, Di, Liuqing |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5304988/ https://www.ncbi.nlm.nih.gov/pubmed/28223797 http://dx.doi.org/10.2147/IJN.S120887 |
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