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Transferrin receptor-targeted pH-sensitive micellar system for diminution of drug resistance and targetable delivery in multidrug-resistant breast cancer

The emergence of drug resistance is partially associated with overproduction of transferrin receptor (TfR). To overcome multidrug resistance (MDR) and achieve tumor target delivery, we designed a novel biodegradable pH-sensitive micellar system modified with HAIYPRH, a TfR ligand (7pep). First, the...

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Detalles Bibliográficos
Autores principales: Gao, Wei, Ye, Guihua, Duan, Xiaochuan, Yang, Xiaoying, Yang, Victor C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5304995/
https://www.ncbi.nlm.nih.gov/pubmed/28223798
http://dx.doi.org/10.2147/IJN.S115215