Asparaginyl endopeptidase improves the resistance of microtubule-targeting drugs in gastric cancer through IQGAP1 modulating the EGFR/JNK/ERK signaling pathway

PURPOSE: In recent years, understanding of the role of asparaginyl endopeptidase (AEP) in tumorigenesis has steadily increased. In this study, we investigated whether AEP expression correlates with sensitivity to chemotherapeutic drugs in gastric cancer and explored the mechanism. PATIENTS AND METHO...

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Detalles Bibliográficos
Autores principales: Cui, Yuehong, Li, Qian, Li, Hong, Wang, Yan, Wang, Hongshan, Chen, Weidong, Zhang, Shangmin, Cao, Jian, Liu, Tianshu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2017
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5304996/
https://www.ncbi.nlm.nih.gov/pubmed/28223821
http://dx.doi.org/10.2147/OTT.S125579

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5304996/
https://www.ncbi.nlm.nih.gov/pubmed/28223821
http://dx.doi.org/10.2147/OTT.S125579

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