Aleglitazar, a dual peroxisome proliferator-activated receptor-α and -γ agonist, protects cardiomyocytes against the adverse effects of hyperglycaemia

PURPOSE: To assess the effects of Aleglitazar on hyperglycaemia-induced apoptosis. METHODS: We incubated human cardiomyocytes, cardiomyocytes from cardiac-specific peroxisome proliferator-activated receptor-γ knockout or wild-type mice in normoglycaemic or hyperglycaemic conditions (glucose 25 mM)....

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Detalles Bibliográficos
Autores principales: Chen, Yan, Chen, Hongmei, Birnbaum, Yochai, Nanhwan, Manjyot K, Bajaj, Mandeep, Ye, Yumei, Qian, Jinqiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2017
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5305042/
https://www.ncbi.nlm.nih.gov/pubmed/28111985
http://dx.doi.org/10.1177/1479164116679081

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5305042/
https://www.ncbi.nlm.nih.gov/pubmed/28111985
http://dx.doi.org/10.1177/1479164116679081

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