Th40 cells (CD4(+)CD40(+) Tcells) drive a more severe form of Experimental Autoimmune Encephalomyelitis than conventional CD4 T cells

CD40-CD154 interaction is critically involved in autoimmune diseases, and CD4 T cells play a dominant role in the Experimental Autoimmune Encephalomyelitis (EAE) model of Multiple Sclerosis (MS). CD4 T cells expressing CD40 (Th40) are pathogenic in type I diabetes but have not been evaluated in EAE....

Descripción completa

Detalles Bibliográficos
Autores principales: Vaitaitis, Gisela M., Yussman, Martin G., Waid, Dan M., Wagner, David H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5305068/
https://www.ncbi.nlm.nih.gov/pubmed/28192476
http://dx.doi.org/10.1371/journal.pone.0172037

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5305068/
https://www.ncbi.nlm.nih.gov/pubmed/28192476
http://dx.doi.org/10.1371/journal.pone.0172037

Ejemplares similares