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Downregulation of Sp1 by Minnelide leads to decrease in HSP70 and decrease in tumor burden of gastric cancer

BACKGROUND: Gastric cancer is the third leading cause of cancer related mortality worldwide with poor survival rates. Even though a number of chemotherapeutic compounds have been used against this disease, stomach cancer has not been particularly sensitive to these drugs. In this study we have evalu...

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Detalles Bibliográficos
Autores principales: Arora, Nivedita, Alsaied, Osama, Dauer, Patricia, Majumder, Kaustav, Modi, Shrey, Giri, Bhuwan, Dudeja, Vikas, Banerjee, Sulagna, Von Hoff, Daniel, Saluja, Ashok
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5305197/
https://www.ncbi.nlm.nih.gov/pubmed/28192510
http://dx.doi.org/10.1371/journal.pone.0171827