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A general method for determining secondary active transporter substrate stoichiometry

The number of ions required to drive substrate transport through a secondary active transporter determines the protein’s ability to create a substrate gradient, a feature essential to its physiological function, and places fundamental constraints on the transporter’s mechanism. Stoichiometry is know...

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Detalles Bibliográficos
Autores principales: Fitzgerald, Gabriel A, Mulligan, Christopher, Mindell, Joseph A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5305207/
https://www.ncbi.nlm.nih.gov/pubmed/28121290
http://dx.doi.org/10.7554/eLife.21016