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Transcription leads to pervasive replisome instability in bacteria
The canonical model of DNA replication describes a highly-processive and largely continuous process by which the genome is duplicated. This continuous model is based upon in vitro reconstitution and in vivo ensemble experiments. Here, we characterize the replisome-complex stoichiometry and dynamics...
Autores principales: | Mangiameli, Sarah M, Merrikh, Christopher N, Wiggins, Paul A, Merrikh, Houra |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5305214/ https://www.ncbi.nlm.nih.gov/pubmed/28092263 http://dx.doi.org/10.7554/eLife.19848 |
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