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Extensive cargo identification reveals distinct biological roles of the 12 importin pathways

Vast numbers of proteins are transported into and out of the nuclei by approximately 20 species of importin-β family nucleocytoplasmic transport receptors. However, the significance of the multiple parallel transport pathways that the receptors constitute is poorly understood because only limited nu...

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Detalles Bibliográficos
Autores principales: Kimura, Makoto, Morinaka, Yuriko, Imai, Kenichiro, Kose, Shingo, Horton, Paul, Imamoto, Naoko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5305215/
https://www.ncbi.nlm.nih.gov/pubmed/28117667
http://dx.doi.org/10.7554/eLife.21184