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Honokiol induces reactive oxygen species-mediated apoptosis in Candida albicans through mitochondrial dysfunction

OBJECTIVE: To investigate the effects of honokiol on induction of reactive oxygen species (ROS), antioxidant defense systems, mitochondrial dysfunction, and apoptosis in Candida albicans. METHODS: To measure ROS accumulation, 2′,7′-dichlorofluorescein diacetate fluorescence was used. Lipid peroxidat...

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Detalles Bibliográficos
Autores principales: Sun, Lingmei, Liao, Kai, Hang, Chengcheng, Wang, Dayong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5305218/
https://www.ncbi.nlm.nih.gov/pubmed/28192489
http://dx.doi.org/10.1371/journal.pone.0172228