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Development of a high-throughput method to evaluate serum bactericidal activity using bacterial ATP measurement as survival readout
Serum Bactericidal Activity (SBA) assay is the method of choice to evaluate the complement-mediated functional activity of both infection- and vaccine-induced antibodies. To perform a typical SBA assay, serial dilutions of sera are incubated with target bacterial strains and complement. The conventi...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5305226/ https://www.ncbi.nlm.nih.gov/pubmed/28192483 http://dx.doi.org/10.1371/journal.pone.0172163 |