Differential inhibitory action of apixaban on platelet and fibrin components of forming thrombi: Studies with circulating blood and in a platelet-based model of thrombin generation

INTRODUCTION: Mechanisms of action of direct oral anticoagulants (DOAC) suggest a potential therapeutic use in the prevention of thrombotic complications in arterial territories. However, effects of DOACs on platelet activation and aggregation have not been explored in detail. We have investigated t...

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Detalles Bibliográficos
Autores principales: Pujadas-Mestres, Lluis, Lopez-Vilchez, Irene, Arellano-Rodrigo, Eduardo, Reverter, Joan Carles, Lopez-Farre, Antonio, Diaz-Ricart, Maribel, Badimon, Juan Jose, Escolar, Gines
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5305231/
https://www.ncbi.nlm.nih.gov/pubmed/28192448
http://dx.doi.org/10.1371/journal.pone.0171486

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5305231/
https://www.ncbi.nlm.nih.gov/pubmed/28192448
http://dx.doi.org/10.1371/journal.pone.0171486

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