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Matrix Metalloproteinases are required for membrane motility and lumenogenesis during Drosophila heart development

Matrix Metalloproteinases (Mmps) degrade glycoproteins and proteoglycans of the extracellular matrix (ECM) or cell surface and are crucial for morphogenesis. Mmps and their inhibitors are expressed during early stages of cardiac development in vertebrates and expression is altered in multiple congen...

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Detalles Bibliográficos
Autores principales: Raza, Qanber S., Vanderploeg, Jessica L., Jacobs, J. Roger
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5305246/
https://www.ncbi.nlm.nih.gov/pubmed/28192468
http://dx.doi.org/10.1371/journal.pone.0171905