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The nanoscale spatial organization of B-cell receptors on immunoglobulin M– and G–expressing human B-cells

B-cell activation is initiated by the binding of antigen to the B-cell receptor (BCR). Here we used dSTORM superresolution imaging to characterize the nanoscale spatial organization of immunoglobulin M (IgM) and IgG BCRs on the surfaces of resting and antigen-­activated human peripheral blood B-cell...

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Detalles Bibliográficos
Autores principales: Lee, Jinmin, Sengupta, Prabuddha, Brzostowski, Joseph, Lippincott-Schwartz, Jennifer, Pierce, Susan K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5305258/
https://www.ncbi.nlm.nih.gov/pubmed/27974642
http://dx.doi.org/10.1091/mbc.E16-06-0452