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Fidgetin regulates cultured astrocyte migration by severing tyrosinated microtubules at the leading edge

Microtubule (MT) organization is essential for many cellular events, including mitosis, migration, and cell polarity. Fidgetin (Fign), an ATP-dependent, MT-severing protein, contributes to the regulation of MT configuration by cutting and trimming MT polymers. Functions of Fign have been indicated i...

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Detalles Bibliográficos
Autores principales: Hu, Zunlu, Feng, Jie, Bo, Weijuan, Wu, Ronghua, Dong, Zhangji, Liu, Yan, Qiang, Liang, Liu, Mei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5305261/
https://www.ncbi.nlm.nih.gov/pubmed/27974640
http://dx.doi.org/10.1091/mbc.E16-09-0628