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Fidgetin regulates cultured astrocyte migration by severing tyrosinated microtubules at the leading edge
Microtubule (MT) organization is essential for many cellular events, including mitosis, migration, and cell polarity. Fidgetin (Fign), an ATP-dependent, MT-severing protein, contributes to the regulation of MT configuration by cutting and trimming MT polymers. Functions of Fign have been indicated i...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The American Society for Cell Biology
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5305261/ https://www.ncbi.nlm.nih.gov/pubmed/27974640 http://dx.doi.org/10.1091/mbc.E16-09-0628 |