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Effect of mutation mechanisms on variant composition and distribution in Caenorhabditis elegans

Genetic diversity is maintained by continuing generation and removal of variants. While examining over 800,000 DNA variants in wild isolates of Caenorhabditis elegans, we made a discovery that the proportions of variant types are not constant across the C. elegans genome. The variant proportion is d...

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Detalles Bibliográficos
Autores principales: Hwang, Ho-Yon, Wang, Jiou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5305269/
https://www.ncbi.nlm.nih.gov/pubmed/28135268
http://dx.doi.org/10.1371/journal.pcbi.1005369