β-Integrin de-phosphorylation by the Density-Enhanced Phosphatase DEP-1 attenuates EGFR signaling in C. elegans

Density-Enhanced Phosphatase-1 (DEP-1) de-phosphorylates various growth factor receptors and adhesion proteins to regulate cell proliferation, adhesion and migration. Moreover, dep-1/scc1 mutations have been detected in various types of human cancers, indicating a broad tumor suppressor activity. Du...

Descripción completa

Detalles Bibliográficos
Autores principales: Walser, Michael, Umbricht, Christoph Alois, Fröhli, Erika, Nanni, Paolo, Hajnal, Alex
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5305270/
https://www.ncbi.nlm.nih.gov/pubmed/28135265
http://dx.doi.org/10.1371/journal.pgen.1006592

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5305270/
https://www.ncbi.nlm.nih.gov/pubmed/28135265
http://dx.doi.org/10.1371/journal.pgen.1006592

Ejemplares similares