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β-Integrin de-phosphorylation by the Density-Enhanced Phosphatase DEP-1 attenuates EGFR signaling in C. elegans

Density-Enhanced Phosphatase-1 (DEP-1) de-phosphorylates various growth factor receptors and adhesion proteins to regulate cell proliferation, adhesion and migration. Moreover, dep-1/scc1 mutations have been detected in various types of human cancers, indicating a broad tumor suppressor activity. Du...

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Detalles Bibliográficos
Autores principales:	Walser, Michael, Umbricht, Christoph Alois, Fröhli, Erika, Nanni, Paolo, Hajnal, Alex
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5305270/ https://www.ncbi.nlm.nih.gov/pubmed/28135265 http://dx.doi.org/10.1371/journal.pgen.1006592

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