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Binding of DNA-bending non-histone proteins destabilizes regular 30-nm chromatin structure

Why most of the in vivo experiments do not find the 30-nm chromatin fiber, well studied in vitro, is a puzzle. Two basic physical inputs that are crucial for understanding the structure of the 30-nm fiber are the stiffness of the linker DNA and the relative orientations of the DNA entering/exiting n...

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Detalles Bibliográficos
Autores principales: Bajpai, Gaurav, Jain, Ishutesh, Inamdar, Mandar M., Das, Dibyendu, Padinhateeri, Ranjith
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5305278/
https://www.ncbi.nlm.nih.gov/pubmed/28135276
http://dx.doi.org/10.1371/journal.pcbi.1005365