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Binding of DNA-bending non-histone proteins destabilizes regular 30-nm chromatin structure
Why most of the in vivo experiments do not find the 30-nm chromatin fiber, well studied in vitro, is a puzzle. Two basic physical inputs that are crucial for understanding the structure of the 30-nm fiber are the stiffness of the linker DNA and the relative orientations of the DNA entering/exiting n...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5305278/ https://www.ncbi.nlm.nih.gov/pubmed/28135276 http://dx.doi.org/10.1371/journal.pcbi.1005365 |