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Public health impact and economic evaluation of vitamin D-fortified dairy products for fracture prevention in France
SUMMARY: The recommended intake of vitamin D-fortified dairy products can substantially decrease the burden of osteoporotic fractures and seems an economically beneficial strategy in the general French population aged over 60 years. INTRODUCTION: This study aims to assess the public health and econo...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer London
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5306172/ https://www.ncbi.nlm.nih.gov/pubmed/27757506 http://dx.doi.org/10.1007/s00198-016-3786-1 |
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author | Hiligsmann, M. Burlet, N. Fardellone, P. Al-Daghri, N. Reginster, J.-Y. |
author_facet | Hiligsmann, M. Burlet, N. Fardellone, P. Al-Daghri, N. Reginster, J.-Y. |
author_sort | Hiligsmann, M. |
collection | PubMed |
description | SUMMARY: The recommended intake of vitamin D-fortified dairy products can substantially decrease the burden of osteoporotic fractures and seems an economically beneficial strategy in the general French population aged over 60 years. INTRODUCTION: This study aims to assess the public health and economic impact of vitamin D-fortified dairy products in the general French population aged over 60 years. METHODS: We estimated the lifetime health impacts expressed in number of fractures prevented, life years gained, and quality-adjusted life years (QALY) gained of the recommended intake of dairy products in the general French population over 60 years for 1 year (2015). A validated microsimulation model was used to simulate three age cohorts for both women and men (60–69, 70–79, and >80 years). The incremental cost per QALY gained of vitamin D-fortified dairy products compared to the absence of appropriate intake was estimated in different populations, assuming the cost of two dairy products per day in base case. RESULTS: The total lifetime number of fractures decreased by 64,932 for the recommended intake of dairy products in the general population over 60 years, of which 46,472 and 18,460 occurred in women and men, respectively. In particular, 15,087 and 4413 hip fractures could be prevented in women and men. Vitamin D-fortified dairy products also resulted in 32,569 QALYs and 29,169 life years gained. The cost per QALY gained of appropriate dairy intake was estimated at €58,244 and fall below a threshold of €30,000 per QALY gained in women over 70 years and in men over 80 years. CONCLUSION: Vitamin D-fortified dairy products have the potential to substantially reduce the burden of osteoporotic fractures in France and seem an economically beneficial strategy, especially in the general population aged above 70 years. |
format | Online Article Text |
id | pubmed-5306172 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | Springer London |
record_format | MEDLINE/PubMed |
spelling | pubmed-53061722017-02-24 Public health impact and economic evaluation of vitamin D-fortified dairy products for fracture prevention in France Hiligsmann, M. Burlet, N. Fardellone, P. Al-Daghri, N. Reginster, J.-Y. Osteoporos Int Original Article SUMMARY: The recommended intake of vitamin D-fortified dairy products can substantially decrease the burden of osteoporotic fractures and seems an economically beneficial strategy in the general French population aged over 60 years. INTRODUCTION: This study aims to assess the public health and economic impact of vitamin D-fortified dairy products in the general French population aged over 60 years. METHODS: We estimated the lifetime health impacts expressed in number of fractures prevented, life years gained, and quality-adjusted life years (QALY) gained of the recommended intake of dairy products in the general French population over 60 years for 1 year (2015). A validated microsimulation model was used to simulate three age cohorts for both women and men (60–69, 70–79, and >80 years). The incremental cost per QALY gained of vitamin D-fortified dairy products compared to the absence of appropriate intake was estimated in different populations, assuming the cost of two dairy products per day in base case. RESULTS: The total lifetime number of fractures decreased by 64,932 for the recommended intake of dairy products in the general population over 60 years, of which 46,472 and 18,460 occurred in women and men, respectively. In particular, 15,087 and 4413 hip fractures could be prevented in women and men. Vitamin D-fortified dairy products also resulted in 32,569 QALYs and 29,169 life years gained. The cost per QALY gained of appropriate dairy intake was estimated at €58,244 and fall below a threshold of €30,000 per QALY gained in women over 70 years and in men over 80 years. CONCLUSION: Vitamin D-fortified dairy products have the potential to substantially reduce the burden of osteoporotic fractures in France and seem an economically beneficial strategy, especially in the general population aged above 70 years. Springer London 2016-10-18 2017 /pmc/articles/PMC5306172/ /pubmed/27757506 http://dx.doi.org/10.1007/s00198-016-3786-1 Text en © The Author(s) 2016 Open Access This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/), which permits any noncommercial use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. |
spellingShingle | Original Article Hiligsmann, M. Burlet, N. Fardellone, P. Al-Daghri, N. Reginster, J.-Y. Public health impact and economic evaluation of vitamin D-fortified dairy products for fracture prevention in France |
title | Public health impact and economic evaluation of vitamin D-fortified dairy products for fracture prevention in France |
title_full | Public health impact and economic evaluation of vitamin D-fortified dairy products for fracture prevention in France |
title_fullStr | Public health impact and economic evaluation of vitamin D-fortified dairy products for fracture prevention in France |
title_full_unstemmed | Public health impact and economic evaluation of vitamin D-fortified dairy products for fracture prevention in France |
title_short | Public health impact and economic evaluation of vitamin D-fortified dairy products for fracture prevention in France |
title_sort | public health impact and economic evaluation of vitamin d-fortified dairy products for fracture prevention in france |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5306172/ https://www.ncbi.nlm.nih.gov/pubmed/27757506 http://dx.doi.org/10.1007/s00198-016-3786-1 |
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