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A phase III, open label, randomized multicenter controlled trial of oral versus intravenous treosulfan in heavily pretreated recurrent ovarian cancer: a study of the North-Eastern German Society of Gynecological Oncology (NOGGO)

OBJECTIVE: In recurrent ovarian cancer (ROC), there is a high demand on effective therapies with a mild toxicity profile. Treosulfan is an alkylating agent approved as oral (p.o.) and intravenous (i.v.) formulation for the treatment of recurrent ovarian cancer. Data on safety and efficacy for either...

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Detalles Bibliográficos
Autores principales: Sehouli, Jalid, Tomè, Oliver, Dimitrova, Desislava, Camara, Oumar, Runnebaum, Ingo Bernhard, Tessen, Hans Werner, Rautenberg, Beate, Chekerov, Radoslav, Muallem, Mustafa Zelal, Lux, Michael Patrick, Trarbach, Tanja, Gitsch, Gerald
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5306340/
https://www.ncbi.nlm.nih.gov/pubmed/27896440
http://dx.doi.org/10.1007/s00432-016-2307-0