Characterization of degradation and heterozygote balance by simulation of the forensic DNA analysis process

Simulation experiments were used to show the impact of varying extraction efficiency, aliquot proportion, and PCR efficiency on the heterozygote balance of a range of diploid and haploid cells. Reducing either parameters introduces variance. It is well-known that the variance in heterozygote balance...

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Detalles Bibliográficos
Autores principales: Hansson, Oskar, Egeland, Thore, Gill, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2016
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5306348/
https://www.ncbi.nlm.nih.gov/pubmed/27807625
http://dx.doi.org/10.1007/s00414-016-1453-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5306348/
https://www.ncbi.nlm.nih.gov/pubmed/27807625
http://dx.doi.org/10.1007/s00414-016-1453-x

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