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Characterization of degradation and heterozygote balance by simulation of the forensic DNA analysis process
Simulation experiments were used to show the impact of varying extraction efficiency, aliquot proportion, and PCR efficiency on the heterozygote balance of a range of diploid and haploid cells. Reducing either parameters introduces variance. It is well-known that the variance in heterozygote balance...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer Berlin Heidelberg
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5306348/ https://www.ncbi.nlm.nih.gov/pubmed/27807625 http://dx.doi.org/10.1007/s00414-016-1453-x |