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Increased levels of RNA oxidation enhance the reversion frequency in aging pro-apoptotic yeast mutants

Despite recent advances in understanding the complexity of RNA processes, regulation of the metabolism of oxidized cellular RNAs and the mechanisms through which oxidized ribonucleotides affect mRNA translation, and consequently cell viability, are not well characterized. We show here that the level...

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Detalles Bibliográficos
Autores principales: Stirpe, Mariarita, Palermo, Vanessa, Ferrari, Matteo, Mroczek, Seweryn, Kufel, Joanna, Falcone, Claudio, Mazzoni, Cristina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5306349/
https://www.ncbi.nlm.nih.gov/pubmed/27803986
http://dx.doi.org/10.1007/s10495-016-1319-1