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The regulation of the mitochondrial apoptotic pathway by glucocorticoid receptor in collaboration with Bcl-2 family proteins in developing T cells

Glucocorticoids (GC) are important in the regulation of selection and apoptosis of CD4(+)CD8(+) double-positive (DP) thymocytes. The pronounced GC-sensitivity of DP thymocytes, observed earlier, might be due to the combination of classical (genomic) and alternative (non-genomic) glucocorticoid recep...

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Detalles Bibliográficos
Autores principales: Prenek, Lilla, Boldizsár, Ferenc, Kugyelka, Réka, Ugor, Emese, Berta, Gergely, Németh, Péter, Berki, Timea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5306359/
https://www.ncbi.nlm.nih.gov/pubmed/27888447
http://dx.doi.org/10.1007/s10495-016-1320-8