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Biphasic Regulation of p38 MAPK by Serotonin Contributes to the Efficacy of Stimulus Protocols That Induce Long-Term Synaptic Facilitation

The MAPK isoforms ERK and p38 MAPK are believed to play opposing roles in long-term synaptic facilitation (LTF) induced by serotonin (5-HT) in Aplysia. To fully understand their roles, however, it is necessary to consider the dynamics of ERK and p38 MAPK activation. Previous studies determined that...

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Detalles Bibliográficos
Autores principales: Zhang, Yili, Smolen, Paul, Baxter, Douglas A., Byrne, John H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for Neuroscience 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5307297/
https://www.ncbi.nlm.nih.gov/pubmed/28197555
http://dx.doi.org/10.1523/ENEURO.0373-16.2017