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Hematopoietic pannexin 1 function is critical for neuropathic pain

Neuropathic pain symptoms respond poorly to available therapeutics, with most treated patients reporting unrelieved pain and significant impairment in daily life. Here, we show that Pannexin 1 (Panx1) in hematopoietic cells is required for pain-like responses following nerve injury in mice, and a po...

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Detalles Bibliográficos
Autores principales: Weaver, Janelle L., Arandjelovic, Sanja, Brown, Gregory, K. Mendu, Suresh, S. Schappe, Michael, Buckley, Monica W., Chiu, Yu-Hsin, Shu, Shaofang, Kim, Jin K., Chung, Joyce, Krupa, Julia, Jevtovic-Todorovic, Vesna, Desai, Bimal N., Ravichandran, Kodi S., Bayliss, Douglas A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5307344/
https://www.ncbi.nlm.nih.gov/pubmed/28195232
http://dx.doi.org/10.1038/srep42550