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Hematopoietic pannexin 1 function is critical for neuropathic pain
Neuropathic pain symptoms respond poorly to available therapeutics, with most treated patients reporting unrelieved pain and significant impairment in daily life. Here, we show that Pannexin 1 (Panx1) in hematopoietic cells is required for pain-like responses following nerve injury in mice, and a po...
Autores principales: | Weaver, Janelle L., Arandjelovic, Sanja, Brown, Gregory, K. Mendu, Suresh, S. Schappe, Michael, Buckley, Monica W., Chiu, Yu-Hsin, Shu, Shaofang, Kim, Jin K., Chung, Joyce, Krupa, Julia, Jevtovic-Todorovic, Vesna, Desai, Bimal N., Ravichandran, Kodi S., Bayliss, Douglas A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5307344/ https://www.ncbi.nlm.nih.gov/pubmed/28195232 http://dx.doi.org/10.1038/srep42550 |
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