Cargando…

TAZ contributes to pulmonary fibrosis by activating profibrotic functions of lung fibroblasts

Transcriptional coactivator with PDZ-binding motif (TAZ) regulates a variety of biological processes. Nuclear translocation and activation of TAZ are regulated by multiple mechanisms, including actin cytoskeleton and mechanical forces. TAZ is involved in lung alveolarization during lung development...

Descripción completa

Detalles Bibliográficos
Autores principales: Noguchi, Satoshi, Saito, Akira, Mikami, Yu, Urushiyama, Hirokazu, Horie, Masafumi, Matsuzaki, Hirotaka, Takeshima, Hideyuki, Makita, Kosuke, Miyashita, Naoya, Mitani, Akihisa, Jo, Taisuke, Yamauchi, Yasuhiro, Terasaki, Yasuhiro, Nagase, Takahide
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5307361/
https://www.ncbi.nlm.nih.gov/pubmed/28195168
http://dx.doi.org/10.1038/srep42595