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TAZ contributes to pulmonary fibrosis by activating profibrotic functions of lung fibroblasts
Transcriptional coactivator with PDZ-binding motif (TAZ) regulates a variety of biological processes. Nuclear translocation and activation of TAZ are regulated by multiple mechanisms, including actin cytoskeleton and mechanical forces. TAZ is involved in lung alveolarization during lung development...
Autores principales: | Noguchi, Satoshi, Saito, Akira, Mikami, Yu, Urushiyama, Hirokazu, Horie, Masafumi, Matsuzaki, Hirotaka, Takeshima, Hideyuki, Makita, Kosuke, Miyashita, Naoya, Mitani, Akihisa, Jo, Taisuke, Yamauchi, Yasuhiro, Terasaki, Yasuhiro, Nagase, Takahide |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5307361/ https://www.ncbi.nlm.nih.gov/pubmed/28195168 http://dx.doi.org/10.1038/srep42595 |
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